60-second Science

From Drunken Stupor to Sober with One (Hormone) Shot

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Synopsis

We all have our tricks for sobering up after a night of drunken revelry: maybe a pot of black coffee or an ice-cold shower. But for mice in a certain lab in Texas, all it takes is a shot. No, not more alcohol—it’s an injection of a hormone called fibroblast growth factor 21, or FGF21.